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Efzilonkofusp alfa

Fusion Protein

Efzilonkofusp alfa is a bispecific Fc fusion protein designed to engage multiple immune pathways. It combines the N-terminal extracellular domain of human CD80 (B7.1) with the Fc fragment of human immunoglobulin G4 (IgG4), linked to an interleukin-2 variant (IL-2v) at its C-terminus. This compound demonstrates significant immunostimulatory effects, acts as an immune checkpoint inhibitor, and exhibits antitumor activity, making it valuable for cancer immunotherapy research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	2922216-50-8
Applications	Fusion Protein
Synonyms	GI-102

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.