Fig. 1 · Structure

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Efzofitimod

NRP2 Antibody

Efzofitimod is a splice variant of the aminoacyl-tRNA synthetase HARS1, fused with the Fc segment of a human antibody, targeting the neuronal phospholipid NRP2 (neuropilin-2). This reagent exhibits significant anti-inflammatory and immunomodulatory properties, effectively downregulating both innate and adaptive immune responses in inflammatory conditions. Its application extends to the suppression of indirect lung disease (ILD), making it a valuable tool for research on inflammatory diseases and immune regulation.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2566615-11-8
Applications NRP2 Antibody
Molecular Weight 64.54 kDa

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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