EG01377 dihydrochloride

Name: EG01377 dihydrochloride
Brand: Adooq Bioscience
SKU: A24483
Rating: 5 (288 reviews)

Catalog No.: A24483

NRP1 inhibitor

EG01377 dihydrochloride is a potent, bioavailable, and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM and IC₅₀ values of 609 nM for both NRP1-a1 and NRP1-b1 domains. It exhibits antiangiogenic, antimigratory, and antitumor activities.

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EG01377 dihydrochloride 2749438-61-5 NRP1 inhibitor

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Grouped product items
Size	Price	Stock
1mg	$108.00	In stock
5mg	$324.00	In stock
10mg	$552.00	In stock
50mg	$1,656.00	In stock
Bulk Size	Bulk Discount

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Biological Activity

Description	EG01377 dihydrochloride is a potent, bioavailable, and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM and IC₅₀ values of 609 nM for both NRP1-a1 and NRP1-b1 domains. It exhibits antiangiogenic, antimigratory, and antitumor activities.

Product Information

Catalog Num	A24483
Formula	C26H32Cl2N6O6S2
Molecular Weight	659.60
CAS Number	2749438-61-5
SMILES	O=S(C1=CC(C2=CC=C(CN)C=C2)=CC3=C1OCC3)(NC4=C(C(N[C@@H](CCC/N=C(N)/N)C(O)=O)=O)SC=C4)=O.Cl.Cl
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 1 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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