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EG36

DnaK Inhibitor

EG36 is a selective inhibitor of E. coli DnaK, specifically targeting its ATPase activity at a concentration of 100 μM. By directly binding to the nucleotide-binding domain (NBD) of DnaK, EG36 disrupts the interaction between DnaK and DnaJ. This unique mechanism provides valuable insights for research on bacterial infectious diseases and their treatment strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2215779-34-1
Applications	DnaK Inhibitor
Formula	C₃₇H₄₁FN₄O₄
Molecular Weight	624.74
SMILES	COC1=CC=CC=C1N2CCC(CN3CCOC4=C(CC5=CC(C(N(CC3)C)=O)=CC=C5)C=C(C=C4)C6=CN=C(C=C6)F)(CC2)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.