EGFR-IN-7

Catalog No.: A18562

EGFR inhibitor

EGFR-IN-7

EGFR-IN-7 Chemical Structure

CAS NO. 2267329-76-8

EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity.

Availability: In stock

Package Price Qty
5 mg
$350.00
10 mg
$650.00
50 mg
$2,000.00
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Biological Activity

EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.4 mL 71.98 mL 143.97 mL
0.5 mM 2.88 mL 14.4 mL 28.79 mL
1 mM 1.44 mL 7.2 mL 14.4 mL
5 mM 0.29 mL 1.44 mL 2.88 mL

*The above data is based on the productmolecular weight 694.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A18562
Actions Inhibitor
M. Wt 694.6
Formula C32H41BrN9O2P
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 2267329-76-8
SMILES CN1CCN(C2CCN(C3=C(C)C=C(NC4=NC=C(Br)C(NC5=CC=C6N=CC=NC6=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1

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