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$0.00 Biological Activity
EGFR-IN-7 (compound 34) is a selective and potent EGFR kinase inhibitor extracted from patent WO2019015655A1, has IC50s of 7.92 nM and 0.218 nM for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) respectively, and shows anti-tumor activity.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 14.4 mL | 71.98 mL | 143.97 mL |
| 0.5 mM | 2.88 mL | 14.4 mL | 28.79 mL |
| 1 mM | 1.44 mL | 7.2 mL | 14.4 mL |
| 5 mM | 0.29 mL | 1.44 mL | 2.88 mL |
*The above data is based on the productmolecular weight 694.6. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| Catalog Num | A18562 |
|---|---|
| Actions | Inhibitor |
| M. Wt | 694.6 |
| Formula | C32H41BrN9O2P |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 3 years Powder |
| CAS No. | 2267329-76-8 |
| SMILES | CN1CCN(C2CCN(C3=C(C)C=C(NC4=NC=C(Br)C(NC5=CC=C6N=CC=NC6=C5P(C)(C)=O)=N4)C(OC)=C3)CC2)CC1 |
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