Fig. 1 · Structure

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EGFR Ligand-Linker Conjugates 4

Anticancer Agent

EGFR Ligand-Linker Conjugates 4 is a conjugate comprising an epidermal growth factor receptor (EGFR) ligand and a linker. This compound is designed for applications in cancer research, particularly in the development of proteolysis-targeting chimeras (PROTACs). It serves as a critical component for synthesizing the EGFR degrader, enabling targeted degradation of EGFR proteins in cellular studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 2654824-18-5
Applications Anticancer Agent
Formula C30H28FN7O2S
Molecular Weight 569.65
SMILES
O=C1C2=C(CN1C(C3=C(CCC4)N4C=N3)C(NC5=NC=CS5)=O)C(F)=CC(C6=CC=C(N7CC8(C7)CNC8)C=C6)=C2

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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