Fig. 1 · Structure
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EGLU
mGluR-2 Antagonist
EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) functions as a potent and competitive antagonist of the mGluR-2 receptor. It exhibits robust interaction with the (lS,3S)-ACPD-sensitive site, characterized by a dissociation constant (Kd) of 66 μM. Due to its interference with mGluR-2 signaling, EGLU has potential applications in research exploring its antidepressant properties.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 170984-72-2 |
| Applications | mGluR-2 Antagonist |
| Formula | C7H13NO4 |
| Molecular Weight | 175.18 |
| Synonyms | (2S)-α-Ethylglutamic acid; (2S)-α-EGLU |
| SMILES | N[C@](CCC(O)=O)(CC)C(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.