Fig. 1 · Structure
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EGR-1-IN-1
EGR-1 Inhibitor
EGR-1-IN-1 is a selective inhibitor of Early Growth Response 1 (EGR-1), demonstrating an IC50 of 1.86 μM. This compound is primarily utilized in the study of inflammatory skin diseases, offering insights into the regulation of EGR-1 in various pathological conditions. Its application aids in understanding the molecular mechanisms underlying skin inflammation, making it valuable for therapeutic research in dermatological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 3077196-25-6 |
| Applications | EGR-1 Inhibitor |
| Formula | C17H13N5O2S |
| Molecular Weight | 351.38 |
| SMILES | COC1=CC2=C(/C(C(N2)=O)=N/NC(NC3=CC=C(C=C3)C#N)=S)C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.