Fig. 1 · Structure
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Eicosapentaenoic acid (metformin)
LC-PUFA
Eicosapentaenoic Acid (EPA) functions as an omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA) with significant biological activity. It exhibits a DNA demethylating capability, facilitating the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Additionally, EPA activates the RAS/ERK/C/EBPβ signaling pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells, thereby enhancing cellular function. The compound also contributes to the relaxation of vascular smooth muscle cells and induces vasodilation, making it relevant for cardiovascular research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1384526-74-2 |
| Applications | LC-PUFA |
| Formula | C24H41N5O2 |
| Molecular Weight | 431.61 |
| Synonyms | EPA (metformin); Timnodonic acid (metformin) |
| SMILES | N=C(N)NC(N(C)C)=N.CC/C=C\C/C=C\C/C=C\C/C=C\C/C=C\CCCC(O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.