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EIDD-1931

anti-virus agent

EIDD-1931 is a novel nucleoside analog and behaves as a potent anti-virus agent.

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Biological Activity

Cellular Effect

Cell Line	Activity	Value	Description	Reference
BHK-21	CC50	5.75 μM	Cytotoxicity against hamster BHK-21 cells incubated for 4 days by MTS assay	[PMID: 36764470]
MDCK	CC50	> 100 μM	Cytotoxicity against MDCK cells assessed as reduction in cell viability measured for 48 hrs by MTT assay	[PMID: 36764470]
Vero	CC50	> 100 μM	Cytotoxicity in African green monkey Vero cells assessed as reduction in cell viability measured after 5 days by resazurin dye based assay	[PMID: 33894564]
Vero	CC50	16.5 μM	Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability incubated for 24 hrs by MTT assay	[PMID: 36764470]
Vero C1008	CC50	> 10 μM	Cytotoxicity against African green monkey Vero E6 cells infected with SARS CoV-2 clinical isolate 2019-nCoV/USA-WA1/2020 incubated for 48 hrs by CellTiter-Glo assay	[PMID: 33186044]

Specifications

Manufacturer	Adooq Bioscience
CAS Number	3258-02-4
Applications	anti-virus agent
Formula	C₉H₁₃N₃O₆
Molecular Weight	259.22
Synonyms	BHC; EIDD-2801 metabolite; NHC
SMILES	O[C@@H]1[C@@H](CO)O[C@](N2C(N=C(NO)C=C2)=O)([H])[C@@H]1O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.