eIF4A3-IN-1

Catalog No.: A12956

eIF4A3 inhibitor

eIF4A3-IN-1

eIF4A3-IN-1 Chemical Structure

CAS NO. 2095486-67-0

eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM).

Availability: In stock

Package Price Qty
1 mg
$320.00
5 mg
$960.00
10 mg
$1,600.00
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Biological Activity

eIF4A3-IN-1 (compound 53a) is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor (IC50=0.26 μM; Kd=0.043 μM).
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 16.98 mL 84.91 mL 169.81 mL
0.5 mM 3.4 mL 16.98 mL 33.96 mL
1 mM 1.7 mL 8.49 mL 16.98 mL
5 mM 0.34 mL 1.7 mL 3.4 mL

*The above data is based on the productmolecular weight 588.88. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12956
Actions Inhibitor
CAS No. 2095486-67-0
Formula C29H23BrClN5O2
M. Wt 588.88
Solubility DMSO
Purity >98%
SMILES ClC(C=C1)=CC=C1[[email protected]@H]2N(C(C3=CC=C(Br)C=C3)=O)CCN(C(C4=C(C)N(C5=CC=CC(C#N)=C5)N=C4)=O)C2
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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