Fig. 1 · Structure

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Elarofiban diTFA

Fibrinogen Receptor Antagonist

Elarofiban diTFA is a potent fibrinogen receptor αIIbβ3 (GPIIb/IIIa) antagonist, existing in its salt form with two trifluoroacetic acid (TFA) molecules. This non-peptide compound exhibits highly effective inhibition with an IC50 of 0.15 nM. Elarofiban diTFA is utilized in research related to platelet-mediated thrombotic disorders, offering significant insights into therapeutic strategies for managing blood clotting conditions.

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Specifications

Manufacturer Adooq Bioscience
Actions Antagonist
CAS Number 198958-89-3
Applications Fibrinogen Receptor Antagonist
Formula C26H34F6N4O8
Molecular Weight 644.56
SMILES
O=C(N[C@H](C1=CN=CC=C1)CC(O)=O)[C@H]2CN(CCC2)C(CCC3CCNCC3)=O.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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