Fig. 1 · Structure
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ELOVL6-IN-4
ELOVL6 Inhibitor
ELOVL6-IN-4 is a selective, orally bioavailable inhibitor of elongase of long chain fatty acids 6 (ELOVL6), exhibiting IC50 values of 79 nM and 94 nM for human and mouse ELOVL6, respectively. This compound demonstrates high selectivity against other ELOVL subtypes, including ELOVL1, ELOVL2, ELOVL3, and ELOVL5, making it an effective tool for studying the role of ELOVL6 in lipid metabolism. Its potent inhibition positions ELOVL6-IN-4 as a valuable reagent for research in metabolic disorders and fatty acid elongation pathways.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1170321-92-2 |
| Applications | ELOVL6 Inhibitor |
| Formula | C20H20F3N3O3S |
| Molecular Weight | 439.45 |
| SMILES | FC(F)(F)C(C=C1)=CC=C1NC(N2[C@@]3([H])C[C@@H](C[C@]2([H])CC3)S(=O)(C4=CC=CC=N4)=O)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.