Fig. 1 · Structure
Documents & Downloads
Elsibucol
VCAM1 Inhibitor
Elsibucol is a selective inhibitor of vascular cell adhesion molecule 1 (VCAM1), primarily utilized in research concerning organ transplant rejection. This metabolically stable propanol derivative exhibits antioxidant, anti-inflammatory, and anti-proliferative properties. By lowering blood cholesterol levels and mitigating oxidative stress, Elsibucol reduces inflammatory responses in injured arteries, thereby inhibiting atherosclerosis and promoting endothelial healing following arterial injury.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 216167-95-2 |
| Applications | VCAM1 Inhibitor |
| Formula | C35H54O4S2 |
| Molecular Weight | 602.93 |
| SMILES | O=C(CCCOC1=C(C(C)(C)C)C=C(SC(C)(C)SC2=CC(C(C)(C)C)=C(O)C(C(C)(C)C)=C2)C=C1C(C)(C)C)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.