Fig. 1 · Structure
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Eltoprazine dihydrochloride
5-HT Receptor Modulator
Eltoprazine dihydrochloride is a dual-action modulator of the serotonin receptor system, functioning as an agonist for both 5-HT1A and 5-HT1B receptors while antagonizing the 5-HT2C receptor. This compound has demonstrated notable antiaggressive and anxiolytic properties in preclinical studies. Eltoprazine dihydrochloride is utilized in research investigating anxiety disorders, aggression modulation, and the broader implications of serotonin signaling in neuropsychiatric conditions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Modulator |
| CAS Number | 143485-51-2 |
| Applications | 5-HT Receptor Modulator |
| Formula | C12H18Cl2N2O2 |
| Molecular Weight | 293.19 |
| Synonyms | DU 28853 dihydrochloride |
| SMILES | N1(C2=C3OCCOC3=CC=C2)CCNCC1.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.