Fig. 1 · Structure
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Eltrombopag-13C4
Thrombopoietin Receptor Agonist
Eltrombopag-13C4 is a 13C-labeled analog of Eltrombopag, functioning as a thrombopoietin receptor agonist. It exhibits pronounced platelet-stimulating activity and is primarily utilized in research related to chronic immune thrombocytopenia. In addition to its hematological effects, Eltrombopag-13C4 demonstrates significant inhibitory action against multidrug-resistant Staphylococcus aureus and has been shown to induce apoptosis in liver cancer cells, making it a valuable reagent for studies in hematology and cancer research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1217230-31-3 |
| Applications | Thrombopoietin Receptor Agonist |
| Formula | C2113C4H22N4O4 |
| Molecular Weight | 446.44 |
| Synonyms | SB-497115-13C4 |
| SMILES | O=[13C](/[13C]1=N/NC(C=CC=C2C3=CC(C(O)=O)=CC=C3)=C2O)N(C(C=C4)=CC(C)=C4C)N=[13C]1[13CH3] |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.