Fig. 1 · Structure

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Eltrombopag-d3

Stable Isotope

Eltrombopag-d3 is a deuterium-labeled variant of Eltrombopag, a nonpeptide agonist of the thrombopoietin receptor. This compound exhibits thrombopoietic activity and is utilized in research related to chronic immune thrombocytopenia characterized by low blood platelet counts. Additionally, Eltrombopag has demonstrated efficacy in cardiovascular research and possesses significant inhibitory effects against multidrug-resistant Staphylococcus aureus. It is also known to induce apoptosis in hepatocellular carcinoma cells, making it a valuable tool for cancer research studies.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 1133710-20-9
Applications Stable Isotope
Formula C25H19D3N4O4
Molecular Weight 445.49
Synonyms SB-497115-d3
SMILES
O=C(O)C1=CC(C2=C([2H])C([2H])=C([2H])C(N/N=C3C(C)=NN(C/3=O)C4=CC=C(C(C)=C4)C)=C2O)=CC=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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