Elvitegravir-d5 is a deuterated form of Elvitegravir, a potent integrase inhibitor targeting HIV-1 and HIV-2 strains. It demonstrates impressive inhibitory activity with IC50 values of 0.7 nM, 2.8 nM, and 1.4 nM against HIV-1IIIB, HIV-2EHO, and HIV-2ROD, respectively. This stable isotope is valuable for biochemical and pharmacokinetic studies, offering insights into HIV integrase function and drug metabolism in research applications.
Elvitegravir-d5 is a deuterated form of Elvitegravir, a potent integrase inhibitor targeting HIV-1 and HIV-2 strains. It demonstrates impressive inhibitory activity with IC50 values of 0.7 nM, 2.8 nM, and 1.4 nM against HIV-1IIIB, HIV-2EHO, and HIV-2ROD, respectively. This stable isotope is valuable for biochemical and pharmacokinetic studies, offering insights into HIV integrase function and drug metabolism in research applications.
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