Fig. 1 · Structure
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Embusartan
AT1 Receptor Blocker
Embusartan is an effective AT1 receptor blocker that demonstrates significant brain penetration due to its high lipophilic nature. By inhibiting the binding of angiotensin II to AT1 receptors within the central nervous system, Embusartan plays a pivotal role in studies related to sympathetic hyperactivity and hypertension. Its unique properties make it a valuable tool for investigating cardiovascular and neurological disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 156001-18-2 |
| Applications | AT1 Receptor Blocker |
| Formula | C25H24FN5O3 |
| Molecular Weight | 461.49 |
| Synonyms | BAY 10-6734 |
| SMILES | O=C(C(C=C(CCCC)N1CC2=CC=C(C3=CC=CC=C3C4=NN=NN4)C=C2F)=CC1=O)OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.