Fig. 1 · Structure
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EMD527040
αvβ6 Antagonist
EMD527040 is a potent and highly selective antagonist of the integrin αvβ6, known for its antifibrotic properties. This compound demonstrates significant activity in blocking αvβ6-mediated signaling, making it a valuable tool for research into carcinoma and liver fibrosis. Its unique mechanism also provides insights into therapeutic strategies for fibrotic diseases.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 851333-14-7 |
| Applications | αvβ6 Antagonist |
| Formula | C29H32Cl2N4O5 |
| Molecular Weight | 587.49 |
| SMILES | O=C(O)CC(NC([C@@H](NC(CCCCNC1=NC=CC=C1)=O)COCC2=CC=CC=C2)=O)C3=CC(Cl)=CC(Cl)=C3 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.