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Emodin-d4

Stable Isotope

Emodin-d4 is a deuterium-labeled derivative of emodin, an anthraquinone compound recognized for its interactions with viral spike proteins. It effectively inhibits the engagement of the SARS-CoV spike protein with angiotensin-converting enzyme 2 (ACE2), demonstrating antiviral properties. Emodin also exhibits significant anti-inflammatory and anticancer effects, alongside selective inhibition of 11β-HSD1 with IC50 values of 186 nM for human and 86 nM for mouse enzymes. This reagent is valuable for studies involving metabolic disorders and cellular signaling pathways, particularly in obesity-related research.

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Specifications

Manufacturer	Adooq Bioscience
CAS Number	132796-52-2
Applications	Stable Isotope
Formula	C₁₅H₆D₄O₅
Molecular Weight	274.26
Synonyms	Frangula emodin-d4
SMILES	O=C1C2=C(O)C([2H])=C(C)C([2H])=C2C(C3=C([2H])C(O)=C([2H])C(O)=C31)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.