Empagliflozin

Catalog No.: A12440

Empagliflozin

Empagliflozin Chemical Structure

CAS NO. 864070-44-0

Empagliflozin is a potent, selective sodium glucose co-transporter-2 inhibitor that is in development for the treatment of type 2 diabetes.

Availability: In stock

Package Price Qty
5 mg
$40.00
10 mg
$60.00
50 mg
$80.00
10mM * 1mL in DMSO
$50.00
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Warning Products are for laboratory research use only. Not for human use. We do not sell to patients.
  • CN Koyani, .et al. Empagliflozin Protects Heart From Inflammation and Energy Depletion via AMPK Activation, Pharmacol Res, 2020, May 17;158:104870 PMID: 32434052

Biological Activity

Empagliflozin is a potent, selective sodium glucose co-transporter-2 inhibitor that is in development for the treatment of type 2 diabetes.
Targets
SGLT2 SGLT5 SGLT6 SGLT1 SGLT4
3.1 nM1.1 μM2 μM8.3 μM11 μM
In vitro (25°C) DMSO 88 mg/mL (195.15 mM)
Water Insoluble
Ethanol Insoluble
In vivo 15% Captisol 14 mg/mL
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 22.18 mL 110.89 mL 221.77 mL
0.5 mM 4.44 mL 22.18 mL 44.35 mL
1 mM 2.22 mL 11.09 mL 22.18 mL
5 mM 0.44 mL 2.22 mL 4.44 mL

*The above data is based on the productmolecular weight 450.91. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A12440
CAS No. 864070-44-0
Formula C23H27ClO7
M. Wt 450.91
Purity >98%
SMILES C1COC[[email protected]]1OC2=CC=C(C=C2)CC3=C(C=CC(=C3)[[email protected]]4[[email protected]@H]([[email protected]]([[email protected]@H]([[email protected]](O4)CO)O)O)O)Cl
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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