Fig. 1 · Structure
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Emtricitabine triphosphate
NRT Inhibitor
Emtricitabine triphosphate is the active triphosphate form of Emtricitabine, a nucleoside reverse transcriptase inhibitor (NRTI). It exhibits potent antiviral activity against HIV and HBV by interfering with viral replication through the inhibition of reverse transcriptase. This compound is widely utilized in research focused on antiretroviral therapies and the mechanisms of viral resistance.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 145819-92-7 |
| Applications | NRT Inhibitor |
| Formula | C8H13FN3O12P3S |
| Molecular Weight | 487.19 |
| Synonyms | (-)-Emtricitabine triphosphate |
| SMILES | O=P(O)(OP(O)(OP(O)(O)=O)=O)OC[C@@H]1O[C@H](N2C=C(F)C(N)=NC2=O)CS1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.