Fig. 1 · Structure
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Emzeltrectinib
Tyrosine Kinase Inhibitor
Emzeltrectinib is a potent tyrosine kinase inhibitor that exhibits strong antineoplastic activity by selectively targeting the neurotrophic receptor tyrosine kinase (NTRK) genes. It is primarily utilized in cancer research and therapeutic development for its efficacy in treating tumors associated with NTRK gene fusions. This compound is essential for studies focused on targeted therapies and the molecular mechanisms of oncogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2223678-97-3 |
| Applications | Tyrosine Kinase Inhibitor |
| Formula | C17H15F3N6O |
| Molecular Weight | 376.34 |
| SMILES | FC1=C(C=C(C=C1)F)[C@@H]2N(C3=NC4=C(C(N)=O)C(N)=NN4C=C3)C[C@H](C2)F |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.