Fig. 1 · Structure

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Enalapril-d5 maleate

ACE Inhibitor

Enalapril-d5 maleate is a deuterium-labeled form of Enalapril, functioning as an angiotensin-converting enzyme (ACE) inhibitor. This compound inhibits the ACE enzyme, consequently reducing the production of angiotensin II, leading to vasodilation and decreased blood pressure. Enalapril-d5 maleate is primarily utilized in pharmacokinetic studies and mechanistic research related to cardiovascular diseases and hypertension management.

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Specifications

Manufacturer Adooq Bioscience
CAS Number 349554-02-5
Applications ACE Inhibitor
Formula C24H27D5N2O9
Molecular Weight 497.55
Synonyms MK-421-d5(maleate)
SMILES
O=C(O)[C@H]1N(C([C@H](C)N[C@H](C(OCC)=O)CCC2=C([2H])C([2H])=C([2H])C([2H])=C2[2H])=O)CCC1.O=C(O)/C=C\C(O)=O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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