Fig. 1 · Structure
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Enbezotinib (enantiomer)
Enbezotinib Enantiomer
Enbezotinib (enantiomer) is a selective inhibitor of the RET (REarranged during Transfection) kinase, a critical target in various cancers. This compound demonstrates potent activity in inhibiting RET signaling pathways, making it a valuable tool for research into RET-dependent tumors. Its applications span studies in cancer biology, therapeutic development, and the exploration of resistance mechanisms in tumorigenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2359650-19-2 |
| Applications | Enbezotinib Enantiomer |
| Formula | C21H21FN6O3 |
| Molecular Weight | 424.43 |
| Synonyms | TPX-0046 (enantiomer) |
| SMILES | FC(C=C1CN2C3=NC4=C5C=NN4C=C3O[C@@]6([H])[C@]2([H])CCC6)=CN=C1O[C@H](C)CNC5=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.