Fig. 1 · Structure
Documents & Downloads
Endonuclease VIII
DNA repair enzyme
Endonuclease VIII is a DNA repair enzyme that functions as a bacterial DNA glycosylase/AP lyase, specifically targeting and excising oxidized pyrimidines from DNA. This enzyme effectively removes modified bases such as thymine glycol, uracil glycol, dihydrothymine, and dihydrouracil, thus playing a crucial role in the maintenance of DNA integrity. It is widely employed in research applications focusing on DNA repair mechanisms and the cellular response to oxidative stress.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 118390-70-8 |
| Applications | DNA repair enzyme |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.