Fig. 1 · Structure
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Endoxifen hydrochloride
Cytochrome P450 Inhibitor
Endoxifen hydrochloride, a selective antagonist of estrogen receptors, serves as a significant active metabolite of Tamoxifen, exhibiting enhanced affinity and specificity. In addition to its receptor activity, Endoxifen hydrochloride also functions as a cytochrome P450 inhibitor, effectively inhibiting aromatase activity. This compound is utilized in breast cancer research, facilitating studies on therapeutic efficacy and mechanisms of action in estrogen-dependent tumors.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1197194-41-4 |
| Applications | Cytochrome P450 Inhibitor |
| Formula | C25H28ClNO2 |
| Molecular Weight | 409.95 |
| SMILES | OC1=CC=C(/C(C2=CC=C(OCCNC)C=C2)=C(C3=CC=CC=C3)\CC)C=C1.[H]Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.