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Enokizumab
Enokizumab (MEDI-528) is a monoclonal antibody specifically designed to target interleukin-9 (IL-9). IL-9 plays a critical role in regulating various pathological processes in the respiratory system, including airway inflammation, mucus production, airway hyperresponsiveness, and fibrosis. This regulation is primarily mediated through the proliferation and activation of mast cells within the airways. Enokizumab's mechanism of action focuses on neutralizing IL-9, thereby potentially mitigating its effects on these respiratory conditions. This antibody is pivotal for research focused on the pathophysiology of respiratory diseases and the development of targeted therapies.
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Biological Activity
Product Details
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Antagonist |
| CAS Number | 909875-08-7 |
| Molecular Weight | 145500 |
| Synonyms | MEDI-528 |
Storage
Store lyophilized at -20°C, keep desiccated.
In lyophilized form, the antibody is stable for 36 months.
After reconstitution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.