Fig. 1 · Structure
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Enoxacin-d8 hydrochloride
Stable Isotope
Enoxacin-d8 hydrochloride is a deuterium-labeled derivative of enoxacin, which primarily targets bacterial DNA gyrase and topoisomerase IV, exhibiting inhibitory activities with IC50 values of 126 µg/ml and 26.5 µg/ml, respectively. It functions as a miRNA processing activator, enhancing siRNA-mediated mRNA degradation and promoting the biogenesis of endogenous miRNAs. Additionally, enoxacin exhibits significant antibacterial properties against both gram-positive and gram-negative organisms and serves as a cancer-specific growth inhibitor by facilitating microRNA processing via TAR RNA-binding protein 2 (TRBP). This compound is valuable for applications requiring stable isotopes in biochemical and pharmacological research.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 2930288-95-0 |
| Applications | Stable Isotope |
| Formula | C15H10D8ClFN4O3 |
| Molecular Weight | 364.83 |
| SMILES | O=C(C1=CN(CC)C2=NC(N3C([2H])([2H])C([2H])([2H])NC([2H])([2H])C3([2H])[2H])=C(C=C2C1=O)F)O.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.