Fig. 1 · Structure
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Enpp-1-IN-16
ENPP1 Inhibitor
Enpp-1-IN-16 is a selective inhibitor of the enzyme ecto-nucleotide triphosphate diphosphohydrolase 1 (ENPP1). This compound is significant in cancer research, particularly in tumors with elevated ENPP1 expression and high levels of cytoplasmic DNA. In addition to its application in oncology, Enpp-1-IN-16 may also contribute to the understanding of other conditions associated with ENPP1 dysregulation, including bacterial and viral infections, insulin resistance, type II diabetes, chondrocalcinosis, and various calcification disorders.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2289739-47-3 |
| Applications | ENPP1 Inhibitor |
| Formula | C23H32N4O4 |
| Molecular Weight | 428.52 |
| SMILES | O=C(N1CCC2(CCN(CC2)C3=C4C=C(OC)C(OC)=CC4=NC=N3)C1)OC(C)(C)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.