Fig. 1 · Structure
Documents & Downloads
Enpp-1-IN-22
ENPP1 Inhibitor
Enpp-1-IN-22 is a potent inhibitor of ecto-nucleotide triphosphate diphosphohydrolase-1 (ENPP1), functioning as an orally bioavailable prodrug. This compound exhibits significant antitumor activity, making it valuable for research focused on cancer therapies and the modulation of purinergic signaling pathways. ENPP1 inhibition by Enpp-1-IN-22 provides a promising approach to explore the tumor microenvironment and potential treatment strategies targeting cellular metabolism and proliferation.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2954111-09-0 |
| Applications | ENPP1 Inhibitor |
| Formula | C28H35N2O9P |
| Molecular Weight | 574.56 |
| SMILES | COC1=NC2=NC=CC(OC3=CC=C(CP(OCOC(C(C)(C)C)=O)(OCOC(C(C)(C)C)=O)=O)C=C3)=C2C=C1 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.