Documents & Downloads

Enpp-1-IN-25

ENPP1 Inhibitor

Enpp-1-IN-25 is a potent ENPP1 inhibitor with an IC50 of 8.05 nM, designed to impede cGAMP degradation, thereby activating the intracellular STING pathway. This compound enhances immune cell infiltration within the tumor microenvironment and boosts type I interferon responses, which can improve the antitumor efficacy when combined with anti-PD-L1 antibodies. Enpp-1-IN-25 is a valuable tool for research in cancer immunotherapy, particularly in elucidating the mechanisms of immune modulation in tumors.

Out of Stock

Free Aliquoting for Your Order

Tell us your preferred amount per vial. We’ll confirm the options.

Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	3067908-20-4
Applications	ENPP1 Inhibitor
Formula	C₁₅H₂₁N₅O₄S
Molecular Weight	367.42
SMILES	COC1=C(C2=CC=C1)N=CN=C2N3CCC(CNS(=O)(N)=O)(CC3)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.