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Enpp-1-IN-26

ENPP1 Inhibitor

Enpp-1-IN-26 is a potent inhibitor of ecto-nucleotide triphosphate diphosphohydrolase-1 (ENPP1), exhibiting an IC50 of 0.188 μM. This compound enhances the expression of interferon-beta (IFN-β) in vivo by inhibiting ENPP1's activity in hydrolyzing cGAMP, a key signaling molecule. Enpp-1-IN-26 is applicable in research focused on metastatic breast cancer and may contribute to understanding immune modulation within the tumor microenvironment.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2848714-91-8
Applications	ENPP1 Inhibitor
Formula	C₁₆H₁₂FN₅O₂S
Molecular Weight	357.36
SMILES	FC1=CC2=C(C(NC(CSC3=NC4=NC(OC)=CC=C4N3)=N2)=O)C=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.