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Enpp-1-IN-29

ENPP1 Inhibitor

Enpp-1-IN-29 is a potent and selective inhibitor of ectonucleotide pyrophosphatase/phosphodiesterase 1 (ENPP1), with an exceptional IC50 of 0.05 nM. This compound is valuable for investigating ENPP1's role in cancers characterized by ENPP1 overexpression, including breast cancer and head and neck cancer, as well as in conditions associated with immune dysregulation, such as autoimmune disorders and tumor immune evasion. Its high specificity makes it an important tool for elucidating the biological functions of ENPP1 in various research applications.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2944114-41-2
Applications	ENPP1 Inhibitor
Formula	C₁₈H₁₄F₂N₄O₅S
Molecular Weight	436.39
SMILES	O=C1OCC2=CN=C3N=C(C=CC3=C2N1CC4=C(C=C(S(=O)(N)=O)C=C4F)F)OC

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.