Enpp/Carbonic Anhydrase-IN-1 is a potent inhibitor of ecto-nucleotide triphosphate diphosphohydrolase (ENPP) and carbonic anhydrase, exhibiting IC50 values of 1.36 μM for NPP1, 1.35 μM for NPP2, 3.00 μM for NPP3, 0.88 μM for CA-II, and 1.02 μM for CA-IX. This compound demonstrates significant antiproliferative effects on cancer cells while displaying low cytotoxicity to normal cells. Additionally, Enpp/Carbonic Anhydrase-IN-1 has been shown to induce apoptosis, making it a valuable tool for cancer research and therapeutic investigations.
Enpp/Carbonic Anhydrase-IN-1 is a potent inhibitor of ecto-nucleotide triphosphate diphosphohydrolase (ENPP) and carbonic anhydrase, exhibiting IC50 values of 1.36 μM for NPP1, 1.35 μM for NPP2, 3.00 μM for NPP3, 0.88 μM for CA-II, and 1.02 μM for CA-IX. This compound demonstrates significant antiproliferative effects on cancer cells while displaying low cytotoxicity to normal cells. Additionally, Enpp/Carbonic Anhydrase-IN-1 has been shown to induce apoptosis, making it a valuable tool for cancer research and therapeutic investigations.
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