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Ent-Calquiquelignan E

DGAT1 Inhibitor

Ent-Calquiquelignan E is a selective inhibitor of diacylglycerol acyltransferase 1 (DGAT1), demonstrating an IC50 of 71.5 μM. This flavonoid lignan compound is valuable for studies investigating metabolic disorders and related pathways. Its inhibitory action on DGAT1 may provide insights into lipid metabolism and potential therapeutic approaches for metabolic diseases.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	1292294-31-5
Applications	DGAT1 Inhibitor
Formula	C₂₆H₂₄O₁₀
Molecular Weight	496.46
SMILES	O=C1C2=C(O)C=C(O)C=C2OC(C3=CC(OC)=C(C(OC)=C3)O[C@@H](CO)[C@H](C4=CC=C(C=C4)O)O)=C1

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.