Entacapone

Catalog No.: A10355

COMT inhibitor

Entacapone

Entacapone Chemical Structure

CAS NO. 130929-57-6

Entacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment.

Availability: In stock

Package Price Qty
10 mg
$41.00
25 mg
$81.00
50 mg
$140.00
100 mg
$239.00
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Biological Activity

Entacapone is a specific, potent, peripherally acting catechol-O-methyltransferase (COMT) inhibitor with IC50 of 151 nM for PD treatment.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 32.76 mL 163.78 mL 327.56 mL
0.5 mM 6.55 mL 32.76 mL 65.51 mL
1 mM 3.28 mL 16.38 mL 32.76 mL
5 mM 0.66 mL 3.28 mL 6.55 mL

*The above data is based on the productmolecular weight 305.29. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

Catalog Num A10355
Actions Inhibitor
M. Wt 305.29
Formula C14H15N3O5
Solubility DMSO
Purity >98%
Storage at -20°C 3 years Powder
CAS No. 130929-57-6
SMILES O=C(N(CC)CC)/C(C#N)=C/C1=CC([N+]([O-])=O)=C(O)C(O)=C1

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