Fig. 1 · Structure
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EOS-984
ENT1 Inhibitor
EOS-984 is a highly potent and selective inhibitor of the equilibrative nucleoside transporter 1 (ENT1). By effectively inhibiting the immunosuppressive activity of adenosine, EOS-984 enhances immune cell proliferation. This compound is useful in research focusing on immune modulation and therapeutic approaches for conditions characterized by immune suppression.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 2724937-55-5 |
| Applications | ENT1 Inhibitor |
| Formula | C33H47N3O9 |
| Molecular Weight | 629.74 |
| SMILES | COC1=CC(C(O[C@@H]2CCCOC3=C(C(OC)=CC(C(NCCCN4CCCN(CC4)CC2)=O)=C3)OC)=O)=CC(OC)=C1OC |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.