Fig. 1 · Structure
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Eoxin E4
Metabolite of 14,15-LTC4 and 14,15-LTD4
Eoxin E4 (14,15-LTE4) is a metabolite derived from 14,15-LTC4 and 14,15-LTD4. This compound demonstrates significant biological activity by increasing vascular permeability in human endothelial cell monolayers, exhibiting about 10-fold less potency than LTC4, yet approximately 100-fold greater potency than histamine. Eoxin E4 is valuable for research applications focused on inflammation, vascular biology, and endothelial cell function.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1000852-57-2 |
| Applications | Metabolite of 14,15-LTC4 and 14,15-LTD4 |
| Formula | C23H37NO5S |
| Molecular Weight | 439.61 |
| Synonyms | 14,15-LTE4; EoxE4 |
| SMILES | CCCCC[C@@H]([C@@H](/C=C/C=C/C=C\C/C=C\CCCC(O)=O)SC[C@@H](C(O)=O)N)O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.