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EP 171

TP Receptor/Platelet Activator

EP 171 is a thromboxane A2 (TP) receptor agonist that acts as a human platelet activator. This compound induces significant constriction of guinea pig trachea, effects that can be reversed by the TP receptor antagonist EP 092. EP 171 demonstrates high affinity for TP receptors on intact human platelets, with an IC50 of 2.9 nM, making it a valuable tool for studying platelet activation and related cardiovascular research.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Agonist
CAS Number	122089-44-5
Applications	TP Receptor/Platelet Activator
Formula	C₂₃H₂₉FO₅
Molecular Weight	404.47
SMILES	O=C(CCC/C=C\C[C@@H]1[C@H]([C@]2(CC[C@@]1(O2)[H])[H])/C=C/[C@@H](COC3=CC=C(C=C3)F)O)O

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.