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Ep300/CREBBP-IN-2

Ep300/CREBBP Inhibitor

Ep300/CREBBP-IN-2 is a potent inhibitor of the Ep300 and CREBBP proteins, exhibiting IC50 values of 0.052 μM and 0.148 μM, respectively. This compound demonstrates strong biological activity relevant to cancer research, making it a valuable tool for investigating the roles of these transcriptional coactivators in tumorigenesis and associated pathways. Ep300/CREBBP-IN-2 can facilitate studies aimed at elucidating the mechanistic underpinnings of cancer progression and potential therapeutic strategies.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2259641-59-1
Applications	Ep300/CREBBP Inhibitor
Formula	C₂₆H₂₇F₃N₄O₄
Molecular Weight	516.51
SMILES	O=C([C@@H]1N(C(C2(C3=CC=C(OC)C=C3)CCC(F)(F)CC2)=O)C[C@H](F)C1)NC4=CC=C(NC(C5)=O)C5=N4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.