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Ep300/CREBBP-IN-8

Ep300/CREBBP Inhibitor

Ep300/CREBBP-IN-8 is a potent inhibitor of the Ep300 and CREBBP proteins, exhibiting IC50 values of 0.014 μM and 0.018 μM, respectively. This compound is orally active and demonstrates significant potential in cancer research by targeting critical pathways involved in oncogenesis. Its ability to modulate Ep300/CREBBP activity makes it a valuable tool for investigating the role of these proteins in various cancer models.

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Specifications

Manufacturer	Adooq Bioscience
Actions	Inhibitor
CAS Number	2259641-24-0
Applications	Ep300/CREBBP Inhibitor
Formula	C₂₅H₂₇F₂N₅O₃
Molecular Weight	483.51
SMILES	O=C([C@@H]1N(C(C2(C3=CC=C(OC)C(F)=C3)CCCCC2)=O)C[C@H](F)C1)NC4=CC=C(NN=C5)C5=N4

Storage & Solubility

In Vitro Solubility

Reported Solubility

No reported solubility data are available for this product.

Preparing Stock Solutions

Stock preparation is unavailable for this product molecular weight.

Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.

Storage

Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.