Fig. 1 · Structure
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EphB1-IN-1
EphB1 Inhibitor
EphB1-IN-1 is a selective inhibitor of the EphB1 receptor, demonstrating IC50 values of 3.0 nM, 15 nM, and 220 nM against the EphB1G703C, EphB1T697G, and wild-type EphB1 variants, respectively. This compound is vital for research applications focused on unraveling the role of EphB1 in cellular signaling pathways and its implications in various diseases, including cancer. Its potency and specificity make it an essential tool for studying EphB1-related biological processes.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 1980036-18-7 |
| Applications | EphB1 Inhibitor |
| Formula | C16H12Cl2N4O2 |
| Molecular Weight | 363.20 |
| SMILES | O=C(NC1=CC2=NC=NC(NC3=CC(O)=CC=C3Cl)=C2C=C1)CCl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.