EphB4-IN-2 is a potent tyrosine kinase inhibitor targeting EphB4, with an IC50 value of 1.6 nM in human assays. This compound demonstrates selective inhibition against kinases containing threonine gatekeeper residues, offering a high degree of ligand efficiency. Its application is valuable in research focusing on EphB4-related signaling pathways and associated therapeutic interventions.
EphB4-IN-2 is a potent tyrosine kinase inhibitor targeting EphB4, with an IC50 value of 1.6 nM in human assays. This compound demonstrates selective inhibition against kinases containing threonine gatekeeper residues, offering a high degree of ligand efficiency. Its application is valuable in research focusing on EphB4-related signaling pathways and associated therapeutic interventions.
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