Fig. 1 · Structure
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(+)-Epibatidine dihydrochloride (d-Epibatidine)
nAChR Agonist
Epibatidine dihydrochloride is a potent agonist of nicotinic acetylcholine receptors (nAChRs), significantly influencing neurotransmission and synaptic activity. Its strong affinity for nAChRs makes it a valuable tool for studying cholinergic signaling pathways and their implications in various neurological disorders. This compound is commonly utilized in research aimed at elucidating the roles of nAChRs in addiction, pain modulation, and cognitive functions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Agonist |
| CAS Number | 166374-43-2 |
| Applications | nAChR Agonist |
| Formula | C11H15Cl3N2 |
| Molecular Weight | 281.61 |
| Synonyms | d-Epibatidine |
| SMILES | ClC1=NC=C([C@@H]2[C@]3([H])N[C@](CC3)([H])C2)C=C1.Cl.Cl |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.