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MicroRNA (miRNA) inhibitors are small molecules that interfere with the maturation or activity of miRNAs. These noncoding RNAs of about 22 nucleotides pair with messenger RNAs (mRNAs) and repress their translation or stability. Targapremir-210, MIR96-IN-1 and SID 3712249 are listed as inhibitors of miR-210, miR-96 and miR-544. Other compounds act on the RNA-binding protein LIN28, which blocks let-7 maturation by binding its precursor and directing terminal uridylation. LIN28 inhibitor LI71 and Lin28-let-7a antagonist 1 belong to this group. The set is mixed and also contains compounds with other main targets, such as camptothecin and the peptidylarginine deiminase (PAD) inhibitor Cl-amidine.
