Fig. 1 · Structure
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Epimedokoreanin B
Anticaner/Anti-periodontitis Agent
Epimedokoreanin B is a natural flavonoid targeting cancer and periodontitis with notable anticancer, anti-inflammatory, and antibacterial properties. It effectively inhibits the growth of lung cancer cells by inducing endoplasmic reticulum stress-mediated apoptosis, accompanied by autophagosome accumulation. Additionally, Epimedokoreanin B serves as an anti-periodontitis agent by inhibiting gingipains and suppressing the growth and biofilm formation of Porphyromonas gingivalis. Its multifaceted biological activities make it a valuable compound for research in oncology and dental disease.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 161068-53-7 |
| Applications | Anticaner/Anti-periodontitis Agent |
| Formula | C25H26O6 |
| Molecular Weight | 422.47 |
| SMILES | O=C1C=C(C2=CC(C/C=C(C)\C)=C(O)C(O)=C2)OC3=C(C/C=C(C)\C)C(O)=CC(O)=C13 |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.