Fig. 1 · Structure
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Epipodophyllotoxin acetate
Antineoplastic Agent
Epipodophyllotoxin acetate is a cyclolignan that functions as an antineoplastic agent, exhibiting significant cytotoxic properties. It demonstrates antiviral activity, effectively inhibiting Herpes Simplex Virus (HSV) and Vesicular Stomatitis Virus (VSV) with IC50 values of 0.2 and 0.1 μg/mL, respectively. This compound is utilized in research applications focused on cancer therapeutics and viral pathogenesis.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| CAS Number | 1180-35-4 |
| Applications | Antineoplastic Agent |
| Formula | C24H24O9 |
| Molecular Weight | 456.44 |
| Synonyms | 4-O-Epipodophyllotoxinyl acetate |
| SMILES | O=C1[C@]2([H])[C@H](C3=CC(OC)=C(C(OC)=C3)OC)C4=CC(OCO5)=C5C=C4[C@H]([C@@]2([H])CO1)OC(C)=O |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.