Fig. 1 · Structure
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Epostane
Antiprogestational Agent
Epostane is an antiprogestational agent that acts as a potent inhibitor of 3β-hydroxysteroid dehydrogenase, exhibiting an IC50 of 1.45 nM. This compound effectively blocks ovulation and pregnancy in rat models, making it valuable for research on reproductive biology and hormonal regulation. Its ability to modulate steroid hormone synthesis underscores its potential applications in the study of contraceptive mechanisms and related pharmacological interventions.
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Specifications
| Manufacturer | Adooq Bioscience |
|---|---|
| Actions | Inhibitor |
| CAS Number | 80471-63-2 |
| Applications | Antiprogestational Agent |
| Formula | C22H31NO3 |
| Molecular Weight | 357.49 |
| Synonyms | WIN 32729 |
| SMILES | C[C@@]12[C@@]3(CC[C@]4([H])[C@]2([H])CC[C@]5([C@@]4([H])CC[C@@]5(O)C)C)[C@](O3)(C(O)=C(C1)C#N)C |
Storage & Solubility
In Vitro Solubility
Reported Solubility
No reported solubility data are available for this product.
Preparing Stock Solutions
| Concentration | |
|---|---|
Values use four significant digits. Prepare to the final solution volume; this is not the volume of solvent to add.
Stock preparation is unavailable for this product molecular weight.
Calculated stock concentrations do not establish solvent solubility. Refer to the reported solubility data for experimental guidance.
Storage
Store powder at -20°C, keep desiccated.
In powder form, the chemical is stable for 36 months.
In solution, store at -20°C and use within 1 month to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.